Can Brains Be Insulin Resistant?

Wellness with a Wow

Can Brains Be Insulin Resistant?

“The higher the blood sugar, the high the brain sugar,” says Psychiatrist Georgia Ede MD. “If your blood sugar is going too high too often so is your brain sugar. But remember that your insulin will plateau at a certain point.”

A recent study out of BYU has linked lifestyle choice to Alzheimer’s disease. “Growing evidence that the brains in humans with Alzheimer’s disease are deficient in the use of glucose,” tweeted one of our friends, and colleagues, Dr. Lori Shemek PhD.

As the brain becomes more insulin resistant, it can’t take in glucose anymore. Brain insulin resistance is a common and early feature of Alzheimer’s disease, closely tied to cognitive decline and capable of promoting many biological abnormalities in the disorder.

“While swimming in a sea of glucose, your brain can literally starve to death,” says Psychiatrist Georgia Ede MD.

While not affecting neuronal glucose uptake, brain insulin resistance in AD is similar to muscle insulin resistance in Type 2 diabetes (T2D). In both circumstances, insulin is much less able to activate a specific signaling pathway than is normally the case.

 

 

Divabetic’s Diabetes Late Nite podcast guests include Asha Brown, Maximize Your Metabolism Co-Authors Dr. Noel Maclaren and Sunita Singh Maclaren, Trisha Artman, Dana B. Roseman, MPH, CDCES, RDN, Know Diabetes By Heart’s Karen Dawson and Patricia Addie-Gentle RN, CDE.

In 1985, Barbra Streisand returned to her roots with the release of her twenty-fourth album, The Broadway Album. Having decided that Broadway musicals were no longer in the same league as some of the more commercial music dominating the charts in the early ‘70s, Streisand ended up taking an unforeseen fifteen-year break from Broadway and show tunes. This return to her “roots” was a shock to many, worrisome for some, but ultimately a massive success, both critically and commercially.

It’s almost time to raise the curtains again in New York City, says Mayor Bill de Blasio. “Broadway needs to come back, and we will move heaven and earth to bring Broadway back,” he said. New York City’s theaters have been shut down for more than a year, since Mar. 12, 2020.

Throughout the podcast, we will be featuring music from Barbra Streisand’s The Broadway Album courtesy of SONY Music.

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